Air Asia and Nok Air fly between Bangkok Don Muang (DMK) and Nakhon Phanom (KOP). The airport at Nakhon Phanom is located 20km west of the city centre with a taxi into town costing a set price of 100 Baht. Mini-buses also run from Nakhon Phanom airport to the Thai-Laos friendship Bridge and Mukdahan.
Two of the most common means of getting to Nakhon Phanom from Bangkok are by road in private tour buses or government-operated tour buses. These buses start from the central North and Northeastern Bus Terminal (Mo Chit) in Bangkok. The fare for bus travel ranges from 300-850 baht, depending on the type of bus. A more convenient and popular bus is operated by the Transport Authority of Thailand. These VIP air conditioned buses operate under the label 99 or 999. These buses are 24-seaters, with seats as comfortable as seats in the business class of an aeroplane. A toilet is also available inside the bus. The distance between Nakhon Phanom and Bangkok is approximately 740 km. This is about an 11-hour journey. Although it seems long, a bus travelling out of Mo Chit at 19:15 arrives at Nakhon Phanom around 06:30. Buses leaving from Nakhon Phanom to Bangkok at 18:00 arrive at around 05:30.
Friendship Bridge III between Thailand and Laos is now open. It is around 10 km north of town and the Thai-Laos International Bus runs between Nakhon Phanom bus station and Thakhek from 08:00 to 17:30 eight times daily (every 60 – 90 minutes). It is not possible to cross the bridge on foot. Note: you need baht for the bus from Nakhon Phanom to Thakhek. Kip or USD are not accepted. Allow about 1.5 hours for the customs rituals on both side of the bridge. Visa on arrival available on the Laos side. If you enter Thailand from Laos, most nationalities get a 30 day visa exempt entry.